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Please use this identifier to cite or link to this item: http://repositorio.inger.gob.mx/jspui/handle/20.500.12100/17339
Title: Sarcopenia and post-hospital outcomes in older adults: A longitudinal study
metadata.dc.creator: MARIO ULISES PEREZ ZEPEDA
Aldo Sgaravatti
Elsa Dent
Keywords: MEDICINA Y CIENCIAS DE LA SALUD;Ciencias médicas;Ciencias clínicas;Geriatría;Personas mayores;Older adults;Envejecido;Aged;Atrofia muscular;Muscular atrophy;Mortalidad;Mortality;Fuerza muscular;Muscle strength;Sarcopenia;Mexico
metadata.dc.date: 2017
Publisher: Elsevier
Description: Introduction: Sarcopenia poses a significant problem for older adults, yet very little is known about this medical condition in the hospital setting. The aims of this hospital-based study were to determine: (i) the prevalence of sarcopenia; (ii) factors associated with sarcopenia; and (iii) the association of sarcopenia with adverse clinical outcomes post-hospitalisation. Methods: This is a longitudinal analysis of consecutive patients aged ≥70 years admitted to a Geriatric Management and Evaluation Unit (GEMU) ward. Sarcopenia was classified using the European Working Group on Sarcopenia in Older People (EWGSOP) algorithm, which included: handgrip strength, gait speed, and muscle mass using Bioelectrical Impedance Analysis (BIA). Outcomes were assessed at 12-months post-hospital discharge, and included both mortality and admission to a hospital Emergency Department (ED). Kaplan-Meier methods were used to estimate survival, with Cox proportion hazard models then applied. All regression analyses controlled for age, sex, and co-morbidity. Results: 172 patients (72% female) with a mean (SD) age of 85.2 (6.4) years were included. Sarcopenia was present in 69 (40.1%) of patients. Patients with sarcopenia were twice as likely to die in the 12-months post-hospitalisation (HR, 95% CI=2.23, 1.15-4.34), but did not have an increased likelihood of ED admission. Conclusions: Sarcopenia showed an independent association with 12-month post-hospital mortality in older adults. With the new recognition of sarcopenia as a medical condition with its own unique ICD-10-CM code, awareness and diagnosis of sarcopenia in clinical settings is paramount.
URI: http://repositorio.inger.gob.mx/jspui/handle/20.500.12100/17339
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Archives of Gerontology and Geriatrics (0167-4943) Vol. 69 (2017).pdf538.5 kBAdobe PDFView/Open