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http://repositorio.inger.gob.mx/jspui/handle/20.500.12100/17323| Title: | Association of low serum 25-hydroxyvitamin D levels with the frailty syndrome in Mexican community-dwelling elderly |
| metadata.dc.creator: | LUIS MIGUEL FRANCISCO GUTIERREZ ROBLEDO JOSE ALBERTO AVILA FUNES Helene Amieva Celine Meillon JOSE LUIS ACOSTA RODRIGUEZ ANA PATRICIA NAVARRETE REYES NORMA TORRES CARRILLO Jose Francisco Muñoz Valle NORA MAGDALENA TORRES CARRILLO |
| Keywords: | MEDICINA Y CIENCIAS DE LA SALUD;Ciencias médicas;Ciencias clínicas;Geriatría;Personas mayores;Older people;Vitamina D;Vitamin D;Fragilidad;Frailty;México;Mexico |
| metadata.dc.date: | 2016 |
| Publisher: | International Society for the Study of the Aging Male & Taylor and Francis |
| Description: | Objective: Since vitamin D is an important regulator of muscle function, the effect of vitamin D deficiency on frailty syndrome has been recently studied. This cross-sectional study aimed to determine the association between 25(OH)-vitamin D levels and frailty status in Mexican community-dwelling elderly. Methods: Sample of 331 community-dwelling elderly aged 70 or older, a subset of those included in the ""Coyoacán cohort"" were included. 25(OH)-vitamin D assay and frailty status were measured. Results: Mean age was 79.3 years and 54.1% were women. Those classified as frail were more likely to have lower Mini-Mental State Examination score (p = 0.015), more disability for instrumental activities of daily living (p < 0.001) and for activities of daily living (p < 0.001). Serum 25(OH)-vitamin D levels were lower in the frail subgroup when compared with the non-frail one (p < 0.001). Multivariate logistic regression analyses showed a significant association between intermediate tertile [odds ratios (OR) = 4.13; 95% confidence intervals (CI) 2.00-8.56] or insufficient tertile (OR = 8.95; 95% CI 2.41-33.30) of vitamin D levels and frailty even after adjusting for potential confounders. Conclusion: These results suggest that older adults with low 25(OH)-vitamin D levels are associated with the probability to being frail compared with those with sufficient vitamin D levels. |
| URI: | http://repositorio.inger.gob.mx/jspui/handle/20.500.12100/17323 |
| Appears in Collections: | 1. Artículos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Aging Male (1473-0790) Vol. 19 (2016).pdf | 455.96 kB | Adobe PDF | View/Open |