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Muscarinic receptors type 1 and 2 in the preoptic-anterior hypothalamic areas regulate ovulation unequally in the rat oestrous cycle

dc.rights.licensehttp://creativecommons.org/licenses/by/4.0es_MX
dc.creatorYadira L. López Ramírezes_MX
dc.creatorKayro López Ramírezes_MX
dc.creatorISABEL ARRIETA CRUZes_MX
dc.creatorANGELICA FLORES RAMIREZes_MX
dc.creatorLUCIANO MENDOZA GARCESes_MX
dc.creatorRaúl Alejandro Librado Osorioes_MX
dc.creatorROGER GUTIERREZ JUAREZes_MX
dc.creatorROBERTO DOMINGUEZ CASALAes_MX
dc.creatorMARIA ESTHER CRUZ BELTRANes_MX
dc.date2017
dc.date.accessioned2019-04-24T20:54:58Z
dc.date.available2019-04-24T20:54:58Z
dc.identifier.urihttp://repositorio.inger.gob.mx/jspui/handle/20.500.12100/17180
dc.descriptionAbstract: Muscarinic receptors types 1 (m1AChR) and 2 (m2AChR) in the preoptic and anterior hypothalamus areas (POA-AHA) were counted, and the effects of blocking these receptors on spontaneous ovulation were analysed throughout the rat oestrous cycle. Rats in each phase of the oestrous cycle were assigned to the following experiments: (1) an immunohistochemical study of the number of cells expressing m1AChR or m2AChR in the POA-AHA and (2) analysis of the effects of the unilateral blockade of the m1AChR (pirenzepine, PZP) or m2AChR (methoctramine, MTC) on either side of the POA-AHA on the ovulation rate. The number of m2AChR-immunoreactive cells was significantly higher at 09:00 h on each day of the oestrous cycle in the POA-AHA region, while no changes in the expression profile of m1AChR protein were observed. The ovulation rate in rats treated with PZP on the oestrous day was lower than that in the vehicle group. Animals treated on dioestrous-1 with PZP or MTC had a higher ovulation rate than those in the vehicle group. In contrast, on dioestrous-2, the MTC treatment decreased the ovulation rate. These results suggest that m1AChR or m2AChR in the POA-AHA could participate in the regulation of spontaneous ovulation in rats.es_MX
dc.formatAdobe PDFes_MX
dc.languageenges_MX
dc.publisherHindawies_MX
dc.relationhttps://www.hindawi.com/journals/ije/2017/4357080/es_MX
dc.relation.requiresSies_MX
dc.rightsAcceso Abiertoes_MX
dc.sourceInternational Journal of Endocrinology (1687-8345) vol. 2017 (2017)es_MX
dc.subjectMEDICINA Y CIENCIAS DE LA SALUDes_MX
dc.subjectCiencias médicases_MX
dc.subjectCiencias clínicases_MX
dc.subjectFenómenos fisiológicos reproductivoses_MX
dc.subjectReproducciónes_MX
dc.subjectOvulaciónes_MX
dc.subjectReceptores muscarínicos M1es_MX
dc.subjectReceptores muscarínicos M2es_MX
dc.subjectReproductive physiological phenomenaes_MX
dc.subjectReproductiones_MX
dc.subjectOvulationes_MX
dc.subjectReceptor, muscarinic M1es_MX
dc.subjectReceptor, muscarinic M2es_MX
dc.titleMuscarinic receptors type 1 and 2 in the preoptic-anterior hypothalamic areas regulate ovulation unequally in the rat oestrous cyclees_MX
dc.typeArtículoes_MX
dc.audienceResearcherses_MX
dc.creator.idCA1237476es_MX
dc.creator.idCA1237477es_MX
dc.creator.idAICI730724MDFRRS06es_MX
dc.creator.idFORA590608MDFLMN03es_MX
dc.creator.idMEGL740605HDFNRC04es_MX
dc.creator.idCA1237478es_MX
dc.creator.idGUJR600202HOCTRG04es_MX
dc.creator.idDOCR390918HNEMSB09es_MX
dc.creator.idCUBE580129MDFRLS07es_MX
dc.creator.nameIdentifiercaes_MX
dc.creator.nameIdentifiercaes_MX
dc.creator.nameIdentifiercurpes_MX
dc.creator.nameIdentifiercurpes_MX
dc.creator.nameIdentifiercurpes_MX
dc.creator.nameIdentifiercaes_MX
dc.creator.nameIdentifiercurpes_MX
dc.creator.nameIdentifiercurpes_MX
dc.creator.nameIdentifiercurpes_MX


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